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Safety Data
A 1992 research discovered that when methylisothiazolinone and methylchloroisothiazolinone (MI/MCI) are given orally, they're subsequently excreted in urine and feces and mainly not saved in physique tisuses.[7] However, when put on your skin, as much as 62% of the substances remained destined towards the software website 24-hours after publicity, and also the substances destined towards the skin had a 13.1-evening half life. Moreover, the research discovered that "MI/MCI was mildly to extremely poisonous to subjects, and extremely poisonous to rabbits when given orally, and mildly poisonous when applied dermally." The research examined the poisoning in subjects, mice, rabbits, and pets at different amounts, used orally or dermally. The research figured: "Methylisothiazolinone/Methylchloroisothiazolinone might be securely utilized in “rinse-off” items in a focus to not exceed 15 ppm as well as in “leave-on” aesthetic items in a focus to not exceed 7.5 ppm. The reported secure use focus describes a combination comprising 23.3PERCENT Methylisothiazolinone and 76.7% Methylchloroisothiazolinone."
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